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KMID : 1103720180780010030
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Journal of the Korean Society of Radiology
2018 Volume.78 No. 1 p.30 ~ p.34
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Necrotic Bone Involvement in an Adult Afflicted with B-Cell Precursor Acute Lymphoblastic Leukemia Mimicking Osteomyelitis: A Case Report
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Kim Hae-Won
Kwon Soon-Yong
Chong Yo-Sep
Park Jeong-Mi
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Abstract
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A 41-year-old female presented with complaint of left hip and buttock pain. Magnetic resonance imaging (MRI) showed multi-focal bone marrow signal intensity changes in left iliac bone, sacrum and femur with an area of necrosis. The primary radiological differential diagnosis was multi-focal tuberculous osteomyelitis. Subsequent pelvic bone biopsy and bone marrow biopsy confirmed the diagnosis of B-cell precursor acute lymphoblastic leukemia with extensive necrosis, which is infrequent in leukemia. When musculoskeletal symptoms precede peripheral blood abnormalities and MRI scanning reveals multi-focal necrotic lesions rather than diffuse signal change, it can be difficult to identify and/or advance leukemia as differential diagnosis.
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KEYWORD
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Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Necrosis, Magnetic Resonance Imaging
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